巨结肠病
肠神经系统
疾病
医学
多样性（政治）
内科学
政治学
法学
作者
Jonathan D. Windster,Naomi Kakiailatu,Laura E. Kuil,Agne Antanaviciute,Andrea Sacchetti,Katherine C. MacKenzie,Joke Zink,Tsung Wai Kan,Eric M. Bindels,Emma de Pater,Michail Doukas,Thierry van den Bosch,Soheil Yousefi,Tahsin Stefan Barakat,Conny Meeussen,Cornelius E. J. Sloots,René Wijnen,Kaushal Parikh,Werend Boesmans,Veerle Melotte
出处
期刊：Gastroenterology
[Elsevier BV]
日期：2024-12-24
卷期号：168 (5): 965-979.e12
被引量：25
标识
DOI：10.1053/j.gastro.2024.12.011
摘要
Two major enteric glial classes were identified in the pediatric intestine, highlighting the significant postnatal contribution of Schwann-like enteric glia to glial heterogeneity. Crucially, these glial subtypes persist in aganglionic segments of patients with HSCR, offering a new target for their treatment using 5-HT agonists.
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