Cytotoxic Terpenes from the Flowers of Inula japonica against Human Hepatocarcinoma Cells

values of 14.60±1.62 and 22.06±1.34 μM against HepG2 and SMMC-7721 cells, respectively. Furthermore, japonipene B (3) showed significant efficacies of arresting the cell cycle at the S/G2-M stages, inducing mitochondria-mediated apoptosis, and inhibiting cell migration in HepG2 cells.