#6666 RISK FACTORS FOR CHRONIC KIDNEY DISEASE AFTER ACUTE KIDNEY INJURY IN ELDERLY SUBJECTS

Abstract Background and Aims Acute kidney injury (AKI) in the elderly is a fairly frequent phenomenon that is favored by functional changes in the kidney and the impact of many chronic diseases whose incidence increases with age. This exposes this particular population to a higher risk of developing chronic kidney disease (CKD). The risk of developing a new CKD in elderly subjects has been estimated to be 4 times that of the population without an episode of AKI in several studies. Our objective was to identify risk factors in this population Method This is a retrospective descriptive study that included patients over 65 years of age for AKI with recovery of normal renal function between January 2002 and December 2015 and who were followed up to one year after discharge. In order to achieve our objective, we collected data related to the patients' age, history, multitargeted or not, mechanism of AKI, KDIGO stage, glomerular filtration rate (GFR) at hospital discharge, using a pre-designed form. Results Among 93 patients who were followed up 18 had developed CKD with a median delay of 6.5±0.4 months. The sex ratio was 0.93 (M/F). In our population 37% were diabetics; 52 of them were multitargeted and 62 had a GFR < 60 ml/min at discharge. 11 patients had required extra renal purification. The most important mechanism of ARF was pre renal (59.1%). Among the risk factors studied (diabetes, hypertension, use of ESRD, anemia, mechanism of AKI) in our population, only hypertension was statistically significant for the development of AKI. Ten patients among 93 were hypertensive. Conclusion Our results suggest that the development of CKD occurred most often in the first year following an episode of AKI, hence the need for close follow-up at one year in this high-risk population