医学
斑秃
泛秃
类风湿性关节炎
皮肤病科
贾纳斯激酶
社会心理的
托法替尼
脱发
Janus激酶抑制剂
银屑病性关节炎
内科学
精神科
细胞因子
作者
Soundos Youssef,Lindsey Bordone
标识
DOI:10.1016/j.jdcr.2022.08.014
摘要
Alopecia areata (AA) is a noncicatricial form of hair loss. While reversible, AA is characterized by substantial disease burden and psychosocial impairment. Patients currently have no curative therapies to effectively treat their physical and mental concerns. Janus kinase inhibitors (JAKIs) have been showing positive results in several AA trials.1,2 Upadacitinib is a selective JAK-1 inhibitor used to treat moderate to severe rheumatoid arthritis and psoriatic arthritis unresponsive to first-line therapies.
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