Multiparametric MRI Evaluation of Liver Fat and Iron after Glucagon-like Peptide-1 Receptor and Glucagon Receptor Dual-Agonist Treatment in a High-Fat Diet–induced Mouse Model

Ultrahigh-field-strength MRI demonstrated that a glucagon-like peptide-1 receptor and glucagon receptor dual agonist more effectively reduced hepatic fat and similarly reduced hepatic iron levels compared with a monoagonist in a fatty liver mouse model, with imaging findings correlating with histologic findings.