医学
体型指数
四分位数
全国健康与营养检查调查
体质指数
内科学
优势比
横断面研究
逻辑回归
子群分析
置信区间
肥胖
人口学
肥胖的分类
人口
病理
环境卫生
脂肪团
社会学
作者
Xiaowu Liu,Honglei Shi,Yunfeng Shi,Hanping Wei,Xiaoliang Yuan,Jiao Zhang,Tingchun Wu,Zengjun Wang
标识
DOI:10.1007/s11255-023-03917-2
摘要
Abdominal obesity, especially visceral fat, may have negative effects on the development and progression of prostate cancer (PCa). A body shape index (ABSI) can more accurately measure visceral fat accumulation. This study aimed to investigate the association between ABSI and PCa in US adults.11,013 participants were enrolled in the National Health and Nutrition Examination Survey from 2001 to 2018. Weighted multivariate logistic regression analyses were employed to explore the independent relationship between ABSI and PCa. Moreover, restricted cubic spline (RCS) analysis, subgroup analysis, and interaction tests were performed.ABSI was positively associated with the presence of PCa. When comparing the second, third, and fourth ABSI quartile to the lowest quartile, the adjusted odds ratios (95% confidence intervals) for PCa risk were 1.34 (0.77, 2.31), 1.75 (1.03, 3.00), and 1.91 (1.12, 3.27), respectively (p for trend = 0.011). The restricted cubic spline regression analysis did not reveal a non-linear correlation between ABSI and PCa (p for non-linearity = 0.076). Subgroup analysis showed a significant interaction effect in subgroups of different BMI (p for interaction = 0.01).Elevated ABSI is significantly associated with an increased risk of PCa, particularly among individuals who are under/normal weighted or obese.
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