Rh(III)-catalyzed domino annulation strategy to synthesize benzo[c]naphthyridinones from 3-diazooxindoles and isoxazolones

A convenient methodology for the synthesis of benzo[c]naphthyridinone derivatives was developed via Rh(III)-catalyzed and Cu(I)-oxidized annulation of 3-diazooxindoles with 3-aryl-5-isoxazolones. This transformation involves in situ generation of tricyclic core through...