Research progresses of stereotactic body radiotherapy in gynaecological cancers

Stereotactic body radiation therapy(SBRT) is a new technology developed in recent years. The advantage of the technique resides in its ability to provide a high dose to tumor but spare normal tissues to an extent. The use of SBRT in gynecological cancers mainly concentrated in local treatment of pelvic recurrence, para-aortic lymph node metastasis and oligometastatic disease. SBRT boosts to macroscopic recurrences and oligometastatic disease can provide local control and a possibility of long-term disease-free survival in carefully selected patients. However, patients who received SBRT following prior irradiation, despite its tight conformality, were still confronted with significant morbidity. SBRT can be used as an alternative treatment for locally advanced cervical cancer after external-beam radiation therapy in patients who are unsuitable for brachytherapy. Key words: Stereotactic body radiation therapy(SBRT); Gynaecological cancer; Dose fractionation; Efficacy