Comparative analysis of exosome markers and extracellular vesicles between colorectal cancer and cancer-associated normal colonic mucosa

at least 3 separate EV subtypes: exosomes, microvesicles, and apoptotic bodies. 1 During oncogenesis, EVs possess some oncogenic potential of their own content and are increasingly being considered in the category of new cancer biomarkers. 2-7Studies carried out to date show that EVs may be important in the progression of colorectal cancer (CRC). 8Qualitative changes of their content were associated with an accelerated proliferation IntroductIon Exocytosis remains an important phenomenon of extracellular transport in the world of living organisms.This process of biological information exchange between the cells is possible via extracellular vesicles (EVs) that convey biologically active molecules such as proteins, nucleic acids, and lipids.High heterogeneity of EV subpopulations due to the difference in the way they are released from the cell and their morphological parameters allows to distinguish orIGInAL ArtIcLE