Screening for Allosteric Modulators of G Protein‐Coupled Receptors

This chapter contains sections titled: Introduction The Allosteric Ternary Complex Model, Radioligand Binding, and Affinity Beyond Affinity—Functional Assays, Efficacy, and Allosteric Agonism Allosteric Modulator Titration Curves The Impact of Functional Assay Format on Allosteric Modulator Screening Taking Advantage of Structural Understanding of Allosteric Binding Sites Summary and Future Directions References