脉络膜新生血管
小发夹RNA
血管内皮生长因子
腺相关病毒
血管生成
新生血管
还原(数学)
病毒学
生物
医学
视网膜
癌症研究
化学
眼科
核糖核酸
载体(分子生物学)
基因
生物化学
血管内皮生长因子受体
几何学
重组DNA
数学
作者
Anne Louise Askou,Jean‐Antoine Pournaras,Maria Pihlmann Kristensen,Jesper Dyrendom Svalgaard,Yvan Arsenijévic,Corinne Kostic,Toke Bek,Frederik Dagnæs‐Hansen,Jacob Giehm Mikkelsen,Thomas G. Jensen,Thomas J. Corydon
摘要
Strategies leading to the long-term suppression of inappropriate ocular angiogenesis are required to avoid the need for repetitive monthly injections for treatment of diseases of the eye, such as age-related macular degeneration (AMD). The present study aimed to develop a strategy for the sustained repression of vascular endothelial growth factor (VEGF), which is identified as the key player in exudative AMD.
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