Using the experimental values ΔH H exc and ΔS H exc (ΔH N exc and ΔS N exc ) for solid solutions of hydrogen and nitrogen in molybdenum, we calculate the parameters ɛ H M and ɛ N M of interaction between hydrogen (nitrogen) and molybdenum lattice doped with small additives of transition metals M; the values of the activity coefficients on hydrogen and nitrogen γ H M and γ N M , ΔH H, ΔH N, ΔS H, ΔS N; enthalpy (η H M and η N M ) and entropy (σ H M and σ N M ) parameters of interaction over the 1100–1300 K range for alloys of Mo1 − y M y H x and Mo1 − y M y N x types (y = 0.01 and 0.02; x = 0.01 and 0.02).