Salivary steroid assays for screening endocrine function.

Current assessment of endocrine function requires multiple sampling regimens. Salivary studies have the advantage of collection by non-invasive techniques, ease of repetition and findings which accurately reflect circulating steroid concentrations. Since hormone concentrations in saliva are low, these investigations require development of highly sensitive, specific immunoassay techniques. Salivary studies may prove useful in assessing the influence of endocrine factors in depression and sexual dysfunction. Clinical and research applications are being rapidly developed.