Chiral Polypeptide Monolayers from Self-Condensation of Amphiphilic Amino Acid Ester. Effect of Chirality on the Membrane Structure

Abstract A Chiral polypeptide monolayer was prepared by self-condensation of an amphiphilic (S)-serine phenyl ester on an aqueous subphase. The monolayer film gave a two-dimensional structure markedly different from that of racemic analogues, reflecting the effect of molecular recognition of chirality in the lateral self-condensation process.