神经母细胞瘤
基因组学
生物
疾病
免疫疗法
癌症
癌症研究
转化研究
神经科学
癌症免疫疗法
计算生物学
生物信息学
医学
基因组
遗传学
病理
生物技术
基因
细胞培养
作者
Nai-Kong V. Cheung,Michael A. Dyer
出处
期刊:Nature Reviews Cancer
[Springer Nature]
日期:2013-06-01
卷期号:13 (6): 397-411
被引量:567
摘要
Neuroblastoma is a solid tumour that arises from the developing sympathetic nervous system. Over the past decade, our understanding of this disease has advanced tremendously. The future challenge is to apply the knowledge gained to developing risk-based therapies and, ultimately, improving outcome. In this Review we discuss the key discoveries in the developmental biology, molecular genetics and immunology of neuroblastoma, as well as new translational tools for bringing these promising scientific advances into the clinic.
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