抗辐射性
辐射敏感性
化学
体内
放射增敏剂
癌症研究
克隆形成试验
谷胱甘肽
肝细胞癌
分子生物学
生物
细胞培养
细胞凋亡
生物化学
医学
放射治疗
内科学
酶
生物技术
遗传学
作者
Mi Yang,Xixi Wu,Jinlong Hu,Yingqiao Wang,Yin Wang,Longshan Zhang,Weiqiang Huang,Xiaoqing Wang,Nan Li,Liwei Liao,Min Chen,Nanjie Xiao,Yongmei Dai,Huazhen Liang,Wenqi Huang,Yuan Lü,Hua Pan,Lu Li,Longhua Chen,Laiyu Liu
标识
DOI：10.1016/j.jhep.2022.01.009
摘要
Radiotherapy benefits patients with unresectable or advanced hepatocellular carcinoma (HCC), but its effectiveness is hampered by radioresistance. Herein, we uncovered a novel role for copper in promoting the radioresistance of HCCs. This work has revealed new targets and potential treatment strategies that could be used to sensitize HCC to radiotherapy.
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