鸟嘌呤核苷酸交换因子
医学
鸟苷
免疫系统
GTP酶
罗亚
信号转导
功能（生物学）
细胞生物学
免疫学
神经科学
生物
遗传学
作者
Yongchang Yang,Yubin Wu
出处
期刊：International Journal of Pediatrics
[Hindawi Publishing Corporation]
日期：2020-01-26
卷期号：47 (01): 47-50
标识
DOI：10.3760/cma.j.issn.1673-4408.2020.01.012
摘要
Vav-family proteins are guanosine nucleotide exchange factors(GEFs)and one of RhoGEFs family numbers.Vav proteins can influence cell signaling transduction, cytoskeleton recombination and adherence migration in special cells by RhoA, RhoG and Rac-1 pathway.There are 80 kinds of RhoGEFs in mammalian cell.Vav proteins play an important role in hematological system, nervous system, cardiovascular system and immune system.So the function of vav protein in immune system was reviewed in this paper.
Key words:
Vav; Guanosine nucleotide exchange factors; Immune system
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