The usage of fungicides to manage plant diseases in many crops is very significant. Reduced disease control with fungicides can result from several causes including application of insufficient quantity, low effectiveness of the fungicide on the target pathogen, improper timing or method of application and excessive rainfall. Resistance is the evolutionary response of a fungus to threat its survival by the fungicides. Fungicides with single site of action are more prone to develop resistance. The quicker development of resistance and the way to control its loss solely depends both on fungicide and the target fungus. The development of fungicide resistance is complex interactions of factors involving nature of fungicide and target pathogen. Thorough knowledge about the ecology of fungicide resistance pertaining to its development and its management is crucial for ensuring sustainable disease control with fungicides.