胸腺瘤
边缘脑炎
γ-氨基丁酸受体
医学
腺癌
免疫疗法
神经学
抗体
胶质瘤
癌症
胃肠病学
内科学
免疫学
脑炎
自身免疫性脑炎
病理
受体
癌症研究
γ-氨基丁酸受体
病毒
精神科
作者
Xiao-Tao Jia,Pan Yanfang,Zhengli Di,Naibing Gu,Zhiqin Liu,Yu-Ming Kang
标识
DOI:10.1007/s10072-018-3536-6
摘要
Anti-γ-aminobutyric acid-B (GABAB) receptor encephalitis is an autoimmune encephalitis associated with antibodies against neuronal cell surface antigens, which are primarily observed with small-cell lung cancer, melanoma, and thymoma. Here, we first report a case on the association between a relatively frequent cancer, gastric adenocarcinoma (GAC), and a rare GABAB receptor antibody limbic encephalitis. The patient was treated with immunotherapy and combined-drug chemotherapy, which were partially effective in terms of stabilizing the tumor and relieving neurological symptoms. This report indicates that, when patients present with GABAB receptor antibody limbic encephalitis, regular and broad screening for tumors including gastric adenocarcinoma should also be considered.
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