地中海贫血
优势比
医学
置信区间
单变量分析
社会支持
输血
横断面研究
生活质量(医疗保健)
内科学
儿科
物理疗法
多元分析
心理学
病理
护理部
心理治疗师
作者
Koorosh Etemad,Parisa Mohseni,Mohammad Aghighi,Ayad Bahadorimonfared,Razieh Hantooshzadeh,Niloufar Taherpour,Negar Piri,Sahar Sotoodeh Ghorbani,Fatemeh Malek,Fatemeh Kheiry,Azimeh Khodami,Tannaz Valadbeigi,Mahmoud Hajipour
出处
期刊:Hemoglobin
[Informa]
日期:2021-07-04
卷期号:45 (4): 245-249
被引量:6
标识
DOI:10.1080/03630269.2021.1965617
摘要
The β-thalassemias are a group of genetic disorders defined by decreased levels of functional hemoglobin (Hb). In light of pivotal improvements in patient survival, the load of consistent treatment harms patients' quality of life (QOL). This study aimed to determine the QOL in patients with β-thalassemia (β-thal) in Iran and identify associated factors. This cross-sectional study was conducted among 1240 patients with β-thal. Data for this study were obtained from the General, the TranQol (Transfusion-dependent QoL) Standard, and the Multidimensional Scale of Perceived Social Support (MSPSS) questionnaires. The univariate and multivariable linear regression was used in STATA version 14 to identify factors related to QOL. Overall, the QOL score was 103 ± 21.96, and adults had a higher score than children under 15 years old. Emotional health had the highest score (39.96 ± 11.54), and sexual activity in adults (1.87 ± 2.08) and activities related to education in children (10.43 ± 7.46) had the lowest. The multivariable linear regression analysis showed that the age, gender, age of blood transfusion initiation, Hb level, number of underlying diseases, and social support level by family and community significantly impact QOL. In exchange for an increase in comorbidities, patients' QOL decreased by 86.0% [odds ratio (OR) = 0.14, 95% confidence interval (95% CI): 0.04-0.45]. Many factors affecting the QOL can be controlled, so social support, increased Hb levels, regular and timely blood transfusions, and treatment can improve the thalassemia patients' QOL.
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