次氯酸钠
抗菌剂
消毒剂
洗必泰
二氧化氯
化学
变形链球菌
牙本质
嗜酸乳杆菌
臼齿
粪肠球菌
牙科
食品科学
亚氯酸钠
微生物学
益生菌
医学
生物
有机化学
细菌
生物化学
大肠杆菌
基因
遗传学
作者
Tugba Serin Kalay,Yakup Kara,Şengül Alpay Karaoğlu,Sevgi Kolayli
出处
期刊:Combinatorial Chemistry & High Throughput Screening
[Bentham Science]
日期:2021-08-16
卷期号:25 (9): 1427-1436
标识
DOI:10.2174/1386207324666210816121255
摘要
Antimicrobial agents are recommended for disinfection of the cavity following mechanical dental caries removal prior to application of restorative material. There is limited information about stabilized Chlorine Dioxide (ClO2) as a cavity disinfectant.The objective of this study is to determine the antimicrobial activity and effect on dentin bond strength of ClO2 compared to chlorhexidine digluconate (CHX), sodium hypochlorite (NaOCl) and Ethanolic Propolis Extract (EPE).Antimicrobial activities of agents against oral pathogens (Staphylococcus aureus, Enterococcus faecalis, Streptococcus mutans, Lactobacillus acidophilus, Lactobacillus casei, Candida albicans, and Saccharomyces cerevisiae) and analyses of EPE were examined. Seventyfive mandibular third molars were sectioned, prepared and divided into five subgroups (n=15/group). Cavity disinfectants (2% CHX, 2.5% NaOCl, 30% EPE, 0.3% ClO2) were applied to etched dentin prior to adhesive and composite build-up. Shear bond strength (SBS) was evaluated with a universal testing machine at a crosshead speed of 0.5 mm/min. The SBS data were analyzed with One-way Analysis of Variance (ANOVA) and Tukey's post-hoc test (p <0.05). The failure modes were evaluated with a stereomicroscope.It was determined that the compared disinfectants were showed different inhibition zone values against oral pathogens. ClO2 exhibited the highest antimicrobial activity, followed by CHX, NaOCI and EPE, respectively. No statistically significant difference was observed in the SBS values between the disinfectant treated groups and control group. The failure modes were predominantly mixed.The use of 0.3% stabilized ClO2 as a cavity disinfectant agent exhibited high antimicrobial activity against oral pathogens and no adverse effects on SBS to etched dentin.
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