医学
萧条(经济学)
痴呆
冲程(发动机)
人口
糖尿病
风险因素
保护因素
单变量分析
老年学
人口学
内科学
多元分析
疾病
环境卫生
内分泌学
工程类
宏观经济学
社会学
经济
机械工程
作者
Ling-yun Liu,Yanxia Lu,Liang Shen,Chunbo Li,Jin‐Tai Yu,Chua Ru Yuan,Kaisy Xinhong Ye,Yin Xia Chao,Qingshan Shen,Rathi Mahendran,Ee Heok Kua,Dehua Yu,Lei Feng
标识
DOI:10.1016/j.jpsychires.2021.11.041
摘要
The prevalence of dementia has been widely reported, and its potential risk and protective factors are well-characterized. However, there is a scarcity of related information regarding mild cognitive impairment (MCI). Thus this population-based study aimed to determine the prevalences of MCI and its subtypes, as well as to identify the risk and protective factors for MCI in the Chinese elderly population of Singapore. Results showed that the overall prevalence of MCI was 12.5%, while the gender-adjusted prevalence of MCI was 12.3%. Gender was found to be significantly associated with the subtypes of MCI, with males more likely to have amnestic MCI and females more likely to have non-amnestic MCI. Older age, lower educational levels, lower social activity levels, depression, hypertension, hyperlipidemia, diabetes and stroke were found to be risk factors for MCI in univariate analysis. However, multivariable analysis showed that only hypertension and stroke were the significant risk factors for MCI. Higher educational levels and active social engagements were significant protective factors for MCI in multivariable analysis. Age and depression had boundary significant associations with the prevalence of MCI. After adjusting for gender, the influence of hypertension, stroke, social engagement, age and depression on MCI remained unchanged, except that education became a boundary significant lower risk factor of MCI development. In conclusion, this study presented the prevalence, risk and protective factors for MCI among Singaporean Chinese older adults, which facilitates the screening of vulnerable groups for MCI.
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