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HomeRadiologyVol. 307, No. 4 PreviousNext Reviews and CommentaryEditorialIs There a Place for Lymphatic Contrast-enhanced US in Thyroid Cancer?Edward G. Grant , Daniel I. KwonEdward G. Grant , Daniel I. KwonAuthor AffiliationsFrom the Department of Radiology (E.G.G.) and Department of Otolaryngology–Head and Neck Surgery (D.I.K.), Keck School of Medicine, University of Southern California, 1500 San Pablo St, Los Angeles, CA 90033.Address correspondence to E.G.G. (email: [email protected]).Edward G. Grant Daniel I. KwonPublished Online:Apr 4 2023https://doi.org/10.1148/radiol.230560MoreSectionsFull textPDF ToolsImage ViewerAdd to favoritesCiteTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinked In References1. Lim H, Devesa SS, Sosa JA, Check D, Kitahara CM. Trends in thyroid cancer incidence and mortality in the United States, 1974-2013. JAMA 2017;317(13):1338–1348. Crossref, Medline, Google Scholar2. Haugen BR, Alexander EK, Bible KC, et al. 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid 2016;26(1):1–133. Crossref, Medline, Google Scholar3. Angell TE, Kwon DI. Finding the balance on extent of initial thyroidectomy for low-risk papillary thyroid carcinoma. J Clin Endocrinol Metab 2022;108(1):e7–e8. Crossref, Medline, Google Scholar4. Machens A, Holzhausen HJ, Dralle H. Skip metastases in thyroid cancer leaping the central lymph node compartment. Arch Surg 2004;139(1):43–45. Crossref, Medline, Google Scholar5. Zhang Y, Lu YY, Li W, et al. Lymphatic contrast-enhanced US to improve the diagnosis of cervical lymph node metastasis from thyroid cancer. Radiology 2023;307(4):e221265. Link, Google Scholar6. Sontum PC. Physicochemical characteristics of Sonazoid, a new contrast agent for ultrasound imaging. Ultrasound Med Biol 2008;34(5):824–833. Crossref, Medline, Google Scholar7. Minami Y, Kudo M. Contrast-enhanced ultrasonography with Sonazoid in hepatocellular carcinoma diagnosis. Hepatoma Res 2020;6:46. Google Scholar8. Shimazu K, Ito T, Uji K, et al. Identification of sentinel lymph nodes by contrast-enhanced ultrasonography with Sonazoid in patients with breast cancer: a feasibility study in three hospitals. Cancer Med 2017;6(8):1915–1922. Crossref, Medline, Google Scholar9. Bertelsen C, King KG, Swanson M, Duddalwar V, Pepper JP. Contrast-enhanced ultrasound with perflubutane for sentinel lymph node mapping in cutaneous melanoma: a pilot study. Laryngoscope 2019;129(5):1117–1122. Crossref, Medline, Google Scholar10. Cranshaw IM, Carnaille B. Micrometastases in thyroid cancer. An important finding? Surg Oncol 2008;17(3):253–258. Crossref, Medline, Google ScholarArticle HistoryReceived: Mar 4 2023Revision requested: Mar 14 2023Revision received: Mar 16 2023Accepted: Mar 20 2023Published online: Apr 04 2023 FiguresReferencesRelatedDetailsAccompanying This ArticleLymphatic Contrast-enhanced US to Improve the Diagnosis of Cervical Lymph Node Metastasis from Thyroid CancerApr 4 2023RadiologyRecommended Articles Perfluorobutane-enhanced US Helps Differentiate Benign Lymph Nodes from Papillary Thyroid Cancer MetastasesRadiology2023Volume: 307Issue: 4Lymphatic Contrast-enhanced US to Improve the Diagnosis of Cervical Lymph Node Metastasis from Thyroid CancerRadiology2023Volume: 307Issue: 4Why Thyroid Surgeons Are Frustrated with Radiologists: Lessons Learned from Pre- and Postoperative USRadioGraphics2016Volume: 36Issue: 7pp. 2141-2153Thermal Ablation for Small Papillary Thyroid Cancer: A Potential Game ChangerRadiology2021Volume: 300Issue: 1pp. 217-218Surveillance Imaging for Head and Neck Cancer: Some Much-needed Proof of EffectivenessRadiology2023Volume: 307Issue: 2See More RSNA Education Exhibits Ultrasound of the Post-thyroidectomy Neck in Well Differentiated Thyroid Cancer - Pearls and PitfallsDigital Posters2022Where Is The Primary Tumor? Imaging Approach To Cervical Lymph Node Metastases From An Unknown Primary TumorDigital Posters2021Practical Strategies to Improve the Use of PET CT in Thyroid CancerDigital Posters2019 RSNA Case Collection Dedifferentiated Thyroid CancerRSNA Case Collection2020TI-RADS 5 NoduleRSNA Case Collection2022TI-RADS 5 - Papillary Thyroid CarcinomaRSNA Case Collection2022 Vol. 307, No. 4 Metrics Altmetric Score PDF download