化学
抗菌剂
抗菌肽
生物传感器
纳米技术
生化工程
计算生物学
组合化学
生物化学
生物
工程类
有机化学
材料科学
作者
Yasaman Ahmadi,Filippo Savini,Natalie Mutter,Ivan Barišić
标识
DOI:10.1021/acs.analchem.3c03854
摘要
The COVID-19 pandemic has shown how emerging infectious diseases could quickly affect the global health and economy. New pathogens with pandemic potential are also expected to appear soon. Moreover, the large use of antibiotics has led to the development of different so-called "superbugs" capable of escaping all of the current antibiotics. In this context, the early and cost-effective detection of pathogens is crucial to avoid the spreading of new pathogens. Here, we present molecular sensors for the recognition of a broad panel of different bacterial species. The detection is based on the use of bacteria-binding peptides (BBPs) in combination with horseradish peroxidase (HRP). We developed a reliable ELISA-like assay that permits us to study the affinity of different BBPs toward some of the most important bacterial pathogens.
科研通智能强力驱动
Strongly Powered by AbleSci AI