Activatable BODIPY-chromene NIR-II probes with small spectral crosstalk enable high-contrast in vivo bioimaging

We design a novel “crossbreeding” NIR-II dye, which can serve as a platform for activatable NIR-II probes with small spectral crosstalk, thereby succeeding in imaging H 2 O 2 in an APAP-induced liver injury model with high signal-to-background ratio.