Leaching of chemicals from microplastics: A review of chemical types, leaching mechanisms and influencing factors

It is widely known that microplastics are present everywhere and they pose certain risks to the ecosystem and humans which are partly attributed to the leaching of additives and chemicals from them. However, the leaching mechanisms remain insufficiently understood. This review paper aims to comprehensively and critically illustrate the leaching mechanisms in biotic and abiotic environments. It analyzes and synthesizes the factors influencing the leaching processes. It achieves the aims by reviewing >165 relevant scholarly papers published mainly in the past 10 years. According to this review, flame retardants, plasticizers and antioxidants are the three main groups of additives in microplastics with the potentials to disrupt endocrine functions, reproduction, brain development and kidney functions. Upon ingestion, the MPs are exposed to digestive fluids containing enzymes and acids which facilitate their degradation and leaching of chemicals. Fats and oils in the digestive tracts also aid the leaching and transport of these chemicals particularly the fat-soluble ones. Leaching is highly variable depending on chemical properties and bisphenols leach to a larger extent than other endocrine disrupting chemicals. However, the rates of leaching remain poorly understood, owing probably to multiple factors at play. Diffusion and partitioning are two main mechanisms of leaching in biotic and abiotic environments. Photodegradation is more predominant in the latter, generating reactive oxygen species which cause microplastic aging and leaching with minimal destruction of the chemicals leached. Effects of microplastic sizes on leaching are governed by Sherwood number, thickness of aqueous boundary layer and desorption half-life. This review contributes to better understanding of leaching of chemicals from microplastics which affect their ecotoxicities and human toxicity.