Pediatric Urinary Stone Composition in the United States

No AccessJournal of UrologyPediatric Urology1 Jun 2012Pediatric Urinary Stone Composition in the United States J. Scott Gabrielsen, Robert J. Laciak, Elizabeth L. Frank, Molly McFadden, Cory S. Bates, Siam Oottamasathien, Blake D. Hamilton, and M. Chad Wallis J. Scott GabrielsenJ. Scott Gabrielsen Division of Urology, University of Utah School of Medicine, Salt Lake City, Utah , Robert J. LaciakRobert J. Laciak Division of Urology, University of Utah School of Medicine, Salt Lake City, Utah , Elizabeth L. FrankElizabeth L. Frank Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah , Molly McFaddenMolly McFadden Division of Epidemiology, University of Utah School of Medicine, Salt Lake City, Utah , Cory S. BatesCory S. Bates Division of Urology, University of Utah School of Medicine, Salt Lake City, Utah , Siam OottamasathienSiam Oottamasathien Division of Urology, University of Utah School of Medicine, Salt Lake City, Utah , Blake D. HamiltonBlake D. Hamilton Division of Urology, University of Utah School of Medicine, Salt Lake City, Utah , and M. Chad WallisM. Chad Wallis Division of Urology, University of Utah School of Medicine, Salt Lake City, Utah View All Author Informationhttps://doi.org/10.1016/j.juro.2012.01.124AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: The incidence of urolithiasis in children is increasing. However, stone composition studies in this population are limited. We sought to determine the effects of age, gender and geographical location on urinary stone composition in the United States pediatric population. Materials and Methods: We obtained composition analyses for all urinary stones submitted to a reference laboratory between 2000 and 2009. Stones were excluded if the patient was younger than 1 year or older than 18 years. Stone composition was determined by Fourier transform infrared spectroscopy. Logistic regression analysis was performed to determine associations between stone composition frequency and age, gender and geographical region. Results: A total of 5,245 stones were included in our analysis. Calcium was found in 89.2% of stones. The percentage of stones containing calcium oxalate increased, while magnesium ammonium phosphate and ammonium acid urate containing stones decreased with age. Calcium oxalate and magnesium ammonium phosphate containing stones were more common in females, while uric acid stones were more common in males. Additionally, significant differences in stone composition frequency were noted between males and females in specific age groups and between age groups within the same gender. Geographical distribution was not significantly associated with stone composition. Conclusions: This series is the largest analysis to date of urinary stone composition in the pediatric population in the United States. 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Link, Google Scholar © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byRoss S, Masko E, Abern M, Allott E, Routh J, Wiener J, Preminger G, Freedland S and Lipkin M (2013) The Effect of Dietary Sodium and Fructose Intake on Urine and Serum Parameters of Stone Formation in a Pediatric Mouse Model: A Pilot StudyJournal of Urology, VOL. 190, NO. 4S, (1484-1489), Online publication date: 1-Oct-2013. Volume 187Issue 6June 2012Page: 2182-2187 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.Keywordsnephrolithiasispediatricsurinary calculiMetrics Author Information J. Scott Gabrielsen Division of Urology, University of Utah School of Medicine, Salt Lake City, Utah More articles by this author Robert J. Laciak Division of Urology, University of Utah School of Medicine, Salt Lake City, Utah More articles by this author Elizabeth L. Frank Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah More articles by this author Molly McFadden Division of Epidemiology, University of Utah School of Medicine, Salt Lake City, Utah More articles by this author Cory S. Bates Division of Urology, University of Utah School of Medicine, Salt Lake City, Utah More articles by this author Siam Oottamasathien Division of Urology, University of Utah School of Medicine, Salt Lake City, Utah More articles by this author Blake D. Hamilton Division of Urology, University of Utah School of Medicine, Salt Lake City, Utah More articles by this author M. Chad Wallis Division of Urology, University of Utah School of Medicine, Salt Lake City, Utah More articles by this author Expand All Advertisement PDF downloadLoading ...