Objective:To summarize the clinical efficacy and experience of multifunctional thoracentesis and abdominal paracentesis device.Methods:choose the patients with hydrothorax, ascites, or pneumathorax who need to puncture as the targets.And use multifunctional thoracentesis and abdominal paracentesis devices to substitute the traditional needles to carry on puncture.After the puncture succeeds.We aspirate the fluid from the thoracic cavity or the abdominal cavity,inject the drugs, douche or aspirate the gas from the thoracic cavity.Results:A total of 126 patients are punctured with multifunctional thoracentesis and abdominal paracentesis devices, of which punctureing successly and meeting the requirement is 122 patients, the successful rate is 96.83%.Conclusion:The multifunctional thoracentesis and abdominal paracentesis device is wider use, easier master, higher success rate,lower manpower, better efficacy and fewer adverse reaction.