铊
化学
DNA
螯合作用
寡核苷酸
氯化物
DNA损伤
谱线
结晶学
无机化学
光化学
立体化学
有机化学
生物化学
天文
物理
作者
Anna M. Nowicka,Beata Krasnodębska‐Ostręga,Beata Wrzosek,Magdalena Jastrzębska,Monika Sadowska,Marcin Maćkiewicz,Zbigniew Stojek
标识
DOI:10.1002/elan.201300489
摘要
Abstract Biologically important short sequences of DNA were treated with Tl(III) complexes. The chloride complex releases the Tl(III) cation and therefore oxidizes DNA components and at concentrations higher than 50 nM cuts the strands. The cuts are well seen in the EQCM plots. The change in the strand structure is well seen at CD and UV‐Vis spectra. The chelate complexes of Tl(III) do not damage the DNA strands. The SERS spectra were particularly useful in demonstration of the chemical changes and orientation vs. the surface changes of particular groups in the strands after interaction with TlCl 4 − .
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