Biopharmaceutical applications of microbial polysaccharides as materials: A Review

生物制药 多糖 生化工程 胞外多糖 生物技术 化学 生物 生物化学 工程类
作者
Yige Song,Shuxin Li,Gong Hao,Ryan Chak Sang Yip,Hao Chen
出处
期刊:International Journal of Biological Macromolecules [Elsevier BV]
卷期号:239: 124259-124259 被引量:45
标识
DOI:10.1016/j.ijbiomac.2023.124259
摘要

Biological characteristics of natural polymers make microbial polysaccharides an excellent choice for biopharmaceuticals. Due to its easy purifying procedure and high production efficiency, it is capable of resolving the existing application issues associated with some plant and animal polysaccharides. Furthermore, microbial polysaccharides are recognized as prospective substitutes for these polysaccharides based on the search for eco-friendly chemicals. In this review, the microstructure and properties of microbial polysaccharides are utilized to highlight their characteristics and potential medical applications. From the standpoint of pathogenic processes, in-depth explanations are provided on the effects of microbial polysaccharides as active ingredients in the treatment of human diseases, anti-aging, and drug delivery. In addition, the scholarly developments and commercial applications of microbial polysaccharides as medical raw materials are also discussed. The conclusion is that understanding the use of microbial polysaccharides in biopharmaceuticals is essential for the future development of pharmacology and therapeutic medicine.
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