<p>Recurrent Apthous stomatitis (RAS) is a common disease of the oral cavity, affecting about 20% of the world’s population, women are more affected than men, and in the most cases it starts around the first decade of life. The clinical features and characteristics of this disease are easily defined still the etiology and the pathophysiology remain unclear. Clinically, RAS is seen in three forms minor RAS, major RAS, herpetiform RAS, and in HIV patients, the fourth form is seen. There are many treatment modalities present for RAS including first & second line of treatment. The existing article provides a detailed review of the current perceptions and knowledge of the etiology, pathogenesis, and management of RAS. </p>