合成生物学
噬菌体疗法
计算生物学
生物
微生物遗传学
噬菌体展示
药物发现
基因
微生物学
遗传学
噬菌体
生物信息学
大肠杆菌
抗体
作者
Ajay Kumar,Anitha Yadav
出处
期刊:Progress in Molecular Biology and Translational Science
日期:2023-01-01
卷期号:: 61-89
标识
DOI:10.1016/bs.pmbts.2023.03.009
摘要
Synthetic phage analysis has been implemented in progressive various areas of biology, such as genetics, molecular biology, and synthetic biology. Many phage-derived technologies have been altered for developing gene circuits to program biological systems. Due to their extremely potent potency, phages also provide greater medical availability against bacterial agents and bacterial diagnostic agents. Its host specificity and our growing ability to manipulate, them further expand its possibility. New Phages also genetically redesign programmable biomaterials with highly tunable properties. Moreover, new phages are central to powerful directed evolution platforms. It is used to enhance existing biological, functions to create new phages. In other sites, the mining of antibiotics, and the emergence and dissemination of more than one type of drug-resistant microbe, a human health concerns. The major point in controlling and treating microbial infections. At present, genetic modifications and biochemical treatments are used to modify phages. Among these, genetic engineering involves the identification of defective proteins, modification of host bodies, recognized receptors, and disruption of bacterial phage resistance signaling gateways.
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