类有机物
3D生物打印
再生医学
组织工程
干细胞
计算机科学
计算生物学
生物医学工程
细胞生物学
生物
医学
作者
Mariana Cabral,Ke Cheng,Donghui Zhu
出处
期刊:Tissue Engineering Part A
[Mary Ann Liebert]
日期:2024-01-11
标识
DOI:10.1089/ten.tea.2023.0209
摘要
Organoids are 3D in vitro tissue models that are derived from stem cells and can closely mimic the structure and function of human organs. The ability to create organoids that recapitulate the complex cellular architecture of organs has emerged as an innovative technique in biomedical research and drug development. However, traditional methods of organoid culture are time-consuming and often yield low quantities of cells, which has led to the development of 3D bioprinting of organoids from bioinks containing suspended cells and desired scaffolds. A comparison across different organoid-building techniques, focusing on 3D bioprinting and its benefits may be helpful and was yet to be distinguished. The goal of this review is to provide an overview of the current state of 3D bioprinting of organoids and its potential applications in tissue engineering, drug screening, and regenerative medicine.
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