Positional immobilization of Pd nanoparticles and enzymes in hierarchical yolk–shell@shell nanoreactors for tandem catalysis

A hierarchical yolk–shell@shell nanoreactor that spatially positioned Pd nanoparticles and the CALB enzyme in separated domains is constructed, and served as an efficient bifunctional catalyst for the one-pot dynamic kinetic resolution (DKR) reaction of 1-phenylethylamine with excellent activity and selectivity.