化学
抗坏血酸
生物相容性
荧光
检出限
量子产额
线性范围
猝灭(荧光)
碳纤维
选择性
纳米技术
光化学
色谱法
有机化学
催化作用
材料科学
物理
复合数
复合材料
量子力学
食品科学
作者
Weiheng Kong,Di Wu,Guoliang Li,Xuefeng Chen,Peiwei Gong,Zhi‐Wei Sun,Guang Chen,Lian Xia,Jinmao You,Yongning Wu
出处
期刊:Talanta
[Elsevier]
日期:2017-04-01
卷期号:165: 677-684
被引量:67
标识
DOI:10.1016/j.talanta.2017.01.022
摘要
A rapid, facile and ultrasensitive fluorescence sensing system based on nitrogen-doped carbon dots (N-doped CDs) for the detection of ascorbic acid (AA) was developed. The highly photoluminescent N-doped CDs with excellent solubility in water and good biocompatibility were prepared by a one-step hydrothermal synthesis and gave the fluorescence quantum yield of 47%. The addition of AA can intensively suppress the fluorescence of the N-doped CDs through the synergistic effect of the inner filter effect (IFE) and the static quenching effect (SQE). Benefited from the remarkable synergistic effect of IFE and SQE, a facile and ultrasensitive sensor was constructed successfully for AA sensing. The detection procedure was achieved within 2 min. The linear response range of AA was obtained from 10−3 to 10−8 M with a detection limit of 5 nM. This developed method enjoyed many merits including more simplicity, lost cost, high sensitivity, good selectivity, rapid response and excellent biocompatibility. Notably, the proposed fluorescent sensor exhibits excellent performance and applicability for AA determination in human serum and rat brain microdialysate, and may provide a fast yet facile route for AA detection in physiological and pathological fields.
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