Boron Lewis Acids Mediated C(sp3)‐Sulfonylation of Isoindolinone Derivatives

Abstract An efficient boron Lewis acids mediated sulfonylation reaction has been successfully developed for the synthesis of C(sp 3 )‐sulfonylation isoindolinones, utilizing various γ ‐hydroxy lactams and sulfonic nucleophile. The prominent features of the present strategy include wide substrate scope, excellent group tolerability, high atom economy, and moderate to good yields (up to 97 % yield).