药物输送
药品
免疫系统
细胞
血液循环
干细胞
医学
药理学
计算生物学
生物
免疫学
纳米技术
细胞生物学
材料科学
遗传学
传统医学
作者
Luyue Wang,Yu Zhang,Yan Ma,Yujia Zhai,Jianbo Ji,Xiaoye Yang,Guangxi Zhai
标识
DOI:10.1016/j.ijpharm.2023.123069
摘要
The application of variable novel drug delivery system has shown a flowering trend in recent years. Among them, the cell-based drug delivery system (DDS) utilizes the unique physiological function of cells to deliver drugs to the lesion area, which is the most complex and intelligent DDS at present. Compared with the traditional DDS, the cell-based DDS has the potential of prolonged circulation in body. Cellular DDS is expected to be the best carrier to realize multifunctional drug delivery. This paper introduces and analyzes common cellular DDSs such as blood cells, immune cells, stem cells, tumor cells and bacteria as well as relevant research examples in recent years. We hope that this review can provide a reference for future research on cell vectors and promote the innovative development and clinical transformation of cell-based DDS.
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