Electrochemical Conversion of Toluene Derivatives to Aromatic Nitriles Using Water (H2O) and Ammonia (NH3)

Aromatic nitriles are extensively produced chemicals with a wide variety of applications. The high demand of these compounds justifies the search for sustainable synthesis alternatives using renewable energy. Here, an electrochemical oxidation of toluene and xylene derivatives to aromatic nitriles using NH 3 and H 2 O under ambient conditions in a one‐pot, two‐step protocol is reported. In a first step, the toluene derivative is oxidized in the absence of a catalyst to the aldehyde. In the second step, ammonia is added together with LiI as an electrocatalyst to obtain the nitrile. The reaction network and mechanism are investigated using control experiments and cyclic voltammetry.