Gene therapy targeting INa to treat life-threatening arrhythmias: beyond proof-of-concept?

Graphical AbstractFuture perspectives in treating cardiac arrhythmias. Gene therapy is emerging as a promising strategy for treating ventricular arrhythmias, aiming to restore normal sinus rhythms. Current approaches in gene therapy are focused on modifying the underlying electrical disturbances that cause these arrhythmias. Moving beyond proof-of-concept, gene therapy has the potential to provide long-term solutions for patients with life-threatening arrhythmias, offering a hopeful outlook for the future.Open in new tabDownload slide