Calcium(II)‐Catalyzed Chemoselective and Regioselective Epoxide Ring Opening with NH Sulfoximines

Abstract We describe herein a versatile methodology for the synthesis of 1,2‐sulfoximidoyl ethanols thanks to a Ca(NTf 2 ) 2 ‐catalyzed epoxide ring‐opening with NH sulfoximines in 2‐MeTHF at 90 °C. The reaction is regioselective by an attack on the less hindered position of the epoxides. The chemoselectivity is assessed by competition reactions with other nucleophiles.