胆汁酸
2型糖尿病
疾病
医学
肠道菌群
胆固醇
人口
肥胖
糖尿病
脂肪肝
益生菌
生理学
生物
内科学
内分泌学
免疫学
环境卫生
细菌
遗传学
作者
Bhagavathi Sundaram Sivamaruthi,Lim Ai Fern,Dk Siti Najwa Rashidah Pg Hj Ismail,Chaiyavat Chaiyasut
标识
DOI:10.1016/j.biopha.2020.110310
摘要
Recent evidence indicates the use of probiotics in the prevention and treatment of diseases. Probiotics are capable of changing the gut microbiota composition and bile acid synthesis to elicit health benefits such as cholesterol-lowering, weight reduction, and improving insulin sensitivity. The aging population is prone to develop diseases because of their decreased physiological and biological systems. Probiotics are one of the promising supplements that may potentially counteract these detrimental effects. This review will discuss the influence of probiotics on bile acids in different populations-the elderly, obese individuals, and those with hypercholesterolemia, type 2 diabetes, hypertension, and non-alcoholic fatty liver disease.
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