毛茛科
翠雀花
萜类
传统医学
化学
生物
立体化学
植物
医学
作者
Tianpeng Yin,Yuanfeng Yan,Xing Li,Guowei Gong,Wenjun Wang
标识
DOI:10.1016/j.phytol.2020.11.017
摘要
Three new diterpenoid alkaloids (DAs), including two lycaconitine-type C19-DAs tatsiedines A and B (1 and 2) and a vakognavine-type C20-DA tatsiedine C (3), have been isolated from the whole plants of Delphinium tatsienense Franch. (Ranunculaceae), a folk medicine for the treatment of wind-toxin syndrome in China. Their structures were established on the basis of extensive spectroscopic analyses. The isolated compounds were evaluated for their potential anti-inflammatory effects against NO production using LPS-stimulated RAW 264.7 macrophages.
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