医学
不利影响
白癜风
皮肤病科
重症监护医学
多学科团队
多学科方法
皮肤癌
癌症
内科学
社会科学
社会学
护理部
作者
Gloria Juan-Carpena,Juan Carlos Palazón-Cabanes,Mar Blanes-Martínez
标识
DOI:10.1016/j.ad.2021.09.009
摘要
Immune checkpoint inhibitors (ICIs) have significantly advanced the treatment of cancer. They are not, however, free of adverse effects. These effects are called immune-related adverse events (irAEs) and often involve the skin. Most of the information on cutaneous irAEs comes from clinical practice. We therefore conducted a thorough review of the characteristics of cutaneous irAEs, recommendations for treatment, and their association with prognosis. The most common events are exanthema, pruritus, vitiligo, and hair loss, although ICIs can cause a wide range of cutaneous dermatoses. The reported association observed between certain reactions and a favorable response to cancer treatment should be interpreted with caution. Dermatologists should be involved in the multidisciplinary care of patients being treated with ICIs as they have an essential role in the diagnosis and treatment of cutaneous irAEs.
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