Optimization for the Extraction of Intra-polysaccharides from Mycelia of Ganoderma lucidum by the Method of RSA

The extraction process of intra-polysaccharides from mycelia of Ganoderma lucidum was optimized by the method of response surface analysis (RAS).The maximum yields of polysaccharides were up to 10.5 g/kg dry mycelia under the following conditions: extractim temperature 95 ℃;extraction time 3.5 h;mycelia/distilled water 1∶2.5.