Objective To investigate the epidemiological features of the human rhinovirus(HRV)in acute upper respiratory tract infections in Shenzhen.Methods Rhinovirus was detected in 635 clinical swabs by real-time fluorescent quantitative PCR.Results The positie rate of HRV was 18.27%(116/635),most cases(64.66%)were under 7 years old,the detection rate of human rhinovirus in young child was higher,followed by infants and preschool child.The infection rate of human rhinovirus in Spring,Summer and Autumn was significantly higher than that in Winter.Conclusions Human rhinovirus is one of the most important pathogens for acute upper respiratory tract infection in Shenzhen area,showing seasonal feature3s and mainly infect children under 7 years old.