泊马度胺
危险系数
地塞米松
多发性骨髓瘤
沙利度胺
临床终点
胃肠病学
医学
置信区间
随机对照试验
外科
来那度胺
内科学
肿瘤科
作者
Meletios Α. Dimopoulos,Meral Beksac,Luděk Pour,Sosana Delimpasi,Vladimir Vorobyev,Hang Quach,Ivan Spicka,Jakub Radocha,Paweł Robak,Kihyun Kım,Michèle Cavo,Kazuhito Suzuki,Kristin Morris,Farrah Pompilus,Amy Phillips-Jones,Xiaoou L Zhou,Giulia Fulci,Neal Sule,Brandon E. Kremer,Joanna Opalińska
标识
DOI:10.1056/nejmoa2403407
摘要
Triplet or quadruplet therapies incorporating proteasome inhibitors, immunomodulators, and anti-CD38 antibodies have led to prolonged survival among patients with newly diagnosed multiple myeloma; however, most patients have a relapse. Frontline lenalidomide therapy has increased the number of patients with lenalidomide-refractory disease at the time of the first relapse.
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