自愈水凝胶
糖尿病
2型糖尿病
医学
重症监护医学
内分泌学
化学
有机化学
作者
Vivek P. Chavda,Divya Teli,Pankti C. Balar,Majid Davidson,Joanna Bojarska,Dixa Vaghela,Vasso Apostolopoulos
标识
DOI:10.1016/j.colsurfb.2024.113761
摘要
Diabetes is a widespread epidemic that includes a number of comorbid conditions that greatly increase the chance of acquiring other chronic illnesses. Every year, there are significantly more people with diabetes because of the rise in type-2 diabetes prevalence. The primary causes of illness and mortality worldwide are, among these, hyperglycemia and its comorbidities. There has been a lot of interest in the creation of peptide-based hydrogels as a potentially effective platform for the treatment of diabetes and its consequences. Here, we emphasize the use of self-assembled hydrogel formulations and their unique potential for the treatment/management of type-2 diabetes and its consequences. (i.e., wounds). Key aspects covered include the characteristics of self-assembled peptide hydrogels, methods for their preparation, and their pre-clinical and clinical applications in addressing metabolic disorders such as type-2 diabetes.
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