医学
富血小板血浆
真皮
激光器
二氧化碳激光器
泌尿科
外科
内科学
血小板
病理
激光手术
光学
物理
作者
Doaa S. Sayed,Daila M Badary,Rania A Ali,Doaa A E Abou-Taleb
出处
期刊:Dermatologic Surgery
[Ovid Technologies (Wolters Kluwer)]
日期:2023-03-21
卷期号:49 (6): 552-558
标识
DOI:10.1097/dss.0000000000003763
摘要
Striae distensae (SD) or stretch marks are common cutaneous conditions that occur because of the stretching of the dermis.OBJECTIVE To evaluate and compare the efficacy of fractional carbon dioxide (CO 2 ) laser alone versus combined fractional CO 2 laser with platelet-rich plasma (PRP) in SD treatment.Thirty adult female patients with SD (SR and SA) were enrolled. In each patient, a split-lesion design was conducted as follows: pairs of SD on both sides of the midline were selected and allocated to groups A and B. Group A: was treated with combined fractional CO 2 laser with intradermal PRP. Group B: was treated with fractional CO 2 laser alone. Skin biopsies were taken from the lesions before and after treatment for histopathologic evaluation.In group A, a significant excellent improvement of the SD was achieved more than in group B ( p = .007) and the mean of improvement was significantly higher (60.33 ± 26.49) than that in group B (43.80 ± 27.43) ( p -value = .001). Group A was also associated with a more significant dermal deposition of collagen and elastic fibers.Combined fractional CO 2 laser with PRP was more effective than fractional CO 2 laser alone for the treatment of SD.
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