表面等离子共振
表面等离子体子
生物传感器
等离子体子
材料科学
灵敏度(控制系统)
干涉测量
光电子学
光学
分析物
旋光法
椭圆偏振法
纳米技术
物理
薄膜
化学
电子工程
纳米颗粒
物理化学
散射
工程类
作者
Atef Shalabney,Ibrahim Abdulhalim
标识
DOI:10.1002/lpor.201000009
摘要
Abstract Surface plasmon resonance (SPR) sensors have been a mature technology for more than two decades now, however, recent investigations show continuous enhancement of their sensitivity and their lower detection limit. Together with the recent investigations in localized SPR phenomena, extraordinary optical transmission through nanoapertures in metals, and surface‐enhanced spectroscopies, drastic developments are expected to revolutionize the field of optical biosensing. Sensitivity‐enhancement (SE) techniques are reviewed focusing both on the physical transduction mechanisms and the system performance. In the majority of cases the SE is associated with the enhancement of the electromagnetic field overlap integral describing the interaction energy within the analyte. Other important mechanisms are the interaction between plasmons and excitons and between the analyte molecules and the metal surface. The lower detection limit can be reduced significantly if systems with high signal‐to‐noise ratio are used such as common‐path interferometry, ellipsometry or polarimetry systems.
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