Study of quality standard for the Sanhuang Qingre capsules

Objective To establish a qualitative method for identification of Radix et Rhizoma Rhei,Radix Scutellaria,Cortex Phelloderdri Chinensi and develop a method for determination of Baicalin in the Sanhuang Qingre capsules.Methods Radix et Rhizoma Rhei,Radix Scutellaria,Cortex Phelloderdri Chinensis were identified by pharmaeognistical identification,and Radix et Rhizoma Rhei,Cortex phellodendri chinensis were identified by TLC.The quality control of the Baicalin in Sanhuang Qingre capsules was used by HPLC.Results Radix et Rhizoma Rhei,Radix Scutellaria,Cortex Phellodendri Chinensis could be identified by pharmaeognosty.Radix et Rhizoma Rhei,Corex Phellodendri Chinensis could be identified by TLC.Baicalin calibration curve was linear within the range of 62.4-1246 ng(r=0.999 98),and the average recovery of puerarin was 98.29% RSD was 0.23%.The HPLC method can be used to determine the content of Baicalin.Conclusion The method is simple,aecurate,sensitive,reproducible and can be used for quantity control of the Sanhuang Qingre capsules.